Patented
Quadruple
Coating

Technology

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TM

Water Soluble Polymer

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Increased resistance to bile acid

Hyaluronic Acid

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Increased resistance to acid

Porous Particle

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Protection against moisture

Soy-Free Protein

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Protection against air

Double Patented Technology

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Method of Preparing
Quadruple-Coating Probiotics
and Quadruple-Coating
Probiotics Prepared

Functionally hydrated
hyaluronic acid and method of
preparing coating lactic acid
bacteria improving mucosal
adhesive capacity and
having selective antagonism
in microflora

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Inhibition of Salmonella Adhesion

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uncoated

Quadruple -Coated

33%

88%

Intestinal Adhesion

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uncoated

Quadruple -Coated

34%

68%

in case of L. rhamnosus IDCC 3201

Reference: A Quadruple Coating of Probiotics for Enhancing Intestinal Adhesion and Competitive Exclusion of Salmonella Typhimurium, JOURNAL OF MEDICINAL FOOD(2022)

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Survivability Data of Coated and Uncoated Probiotics

Reference: Analysis of Quadruple Coating for Improvement in Improving Gastrointestinal Stability
and Survivability of Probiotics, A quadruple coating of probiotics for enhancing intestinal adhesion
and competitive exclusion of Salmonella Typhimurium, Patent KR10-128032, KR10-1764412

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Stomach

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Small Intestine

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Large Intestine

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TM

Probiotics

Enterococcus faecium IDCC 2102

Streptococcus thermophilus IDCC 2201

Lactococcus lactis IDCC 2301

Lactobacillus gasseri IDCC 3101

Lactobacillus rhamnosus IDCC 3201

Lactobacillus acidophilus IDCC 3302

Lactobacillus casei IDCC 3451

Lactobacillus plantarum IDCC 3501

Lactobacillus salivarius IDCC 3551

Lactobacillus reuteri IDCC 3701

Lactobacillus helveticus IDCC 3801

Lactobacillus fermentum IDCC 3901

Bifidobacterium longum IDCC 4101

Bifidobacterium bifidum IDCC 4201

Bifidobacterium lactis IDCC 4301

Bifidobacterium breve IDCC 4401

Lactobacillus johnsonii IDCC 9203

Spore Forming Strains
without 

Bacillus coagulans IDCC 1201

Bacillus subtilits IDCC 1101

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TM